This reaction is carried out in glacial (anhydrous) acetic acid as the solvent. The acetic acid reacts with 2, 6-dimethylaniline to develop an equilibrium between it and its acetate salt.

You are watching: Why do we add glacial acetic acid

What is the purpose of developing an equilibrium in between 2,6-dimethylaniline and also its salt here?

EDIT:This is the source of the quoted message & the procedure to synthedimension lidocaine : https://tigerweb.towkid.edu/jdiscord/www/332_lab_info/summer2016chem332labs/webexpt_lidocaine_a.pdf


*

I think acetic acid is offered bereason it enables you to play funny games with the varying solubility of reactants, commodities, and byproducts. Keep in mind that the last product is not soluble in acetic acid/water mixture, however the reactants and salt byproducts are. This means that instead of percreating an extract in a separatory funnel (additional step, plus you"ll must evaporate solvent and also purify), you deserve to simply filter the solid product straight from the rest of liquid.

This is the kind of simplifying "magic" you deserve to gain when the process chemists gain a stab at creating how to run the reactivity.


*

Thanks for contributing a solution to slrfc.org Stack Exchange!

Please be certain to answer the question. Provide details and share your research!

But avoid

Asking for aid, clarification, or responding to various other answers.Making statements based upon opinion; earlier them up with referrals or individual experience.

Use MathJax to format equations. MathJax recommendation.

See more: Why Should You Stay Out Of The Open Space To The Right Of A Semi-Tractor-Trailer

To learn even more, view our tips on composing excellent answers.


Article Your Answer Discard

By clicking “Message Your Answer”, you agree to our terms of service, privacy policy and also cookie plan


Not the answer you're looking for? Browse various other questions tagged solubility synthesis or ask your own question.


*

website style / logo © 2021 Stack Exadjust Inc; user contributions licensed under cc by-sa. rev2021.9.2.40142


Chemisattempt Stack Exreadjust functions best through JavaScript enabled
*

Your privacy

By clicking “Accept all cookies”, you agree Stack Exreadjust have the right to store cookies on your device and discshed information in accordance via our Cookie Policy.