Part 1

Which rat had the fastest basal metabolic price (BMR)?

The normal rat had the faster basal metabolic rate, bereason it was not missing its pituitary gland or its thyroid gland also.

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Why did the metabolic rates differ in between the normal rat and also the surgically transformed rats? How well did the results compare via your prediction? The normal rat has the highest possible BMR bereason it has the glands forced to stimulate and control the release of thyroid hormones.

If an animal has actually been thyroidectomized, what hormone(s) would be lacking in its blood? Triiodothyronine and also thyroxine.


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If an animal has actually been hypophysectomized, what result would certainly you intend to check out in the hormone levels in its body? For the hypophysectomized rat, TSH would be lacking as a result of the missing pituitary gland.

Part 2

What was the impact of thyroxine injections on the normal rat’s BMR? The levels were a small off. The normal rat was hyperthyroidic bereason the thyroxine rises the metabolic price but it did not develop a goiter.


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What was the effect of thyroxine injections on the thyroidectomized rat’s BMR? How does the BMR in this instance compare through the normal rat’s BMR? Was the dose of thyroxine in the syringe as well big, too small, or simply right? The BMR increased for the thyroidectomized rat through the thyroxine injections.


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The BMR was still a tiny little under the normal rat’s BMR with thyroxine. The dose was too low.

What was the result of thyroxine injections on the hypophysectomized rat’s BMR? How does the BMR in this instance compare via the normal rat’s BMR? Was the dose of thyroxine in the syringe also large, too little, or just right? The BMR raised for the hypophysectomized rat through the thyroxine injections. The BMR was still a little bit under the normal rat’s BMR through thyroxine. The dose was as well low

Part 3

What was the impact of thyroid-stimulating hormone (TSH) injections on the normal rat’s BMR? The result of TSH wregarding boost the normal rat’s BMR

What was the impact of TSH injections on the thyroidectomized rat’s BMR? How does the BMR in this instance compare through the normal rat’s BMR? Why was this result observed? There was no effect on the thyroidectomized rat’s BMR with the injection of TSH because tright here was no thyroid gland to stimulate. What was the impact of TSH injections on the hypophysectomized rat’s BMR? How does the BMR in this case compare through the normal rat’s BMR? Was the dose of TSH in the syringe also large, too tiny, or just right? The hypophysectomized rat’s BMR enhanced with TSH. The BMR was simply listed below the normal rat’s BMR however still lower. The syringe amount was a tiny too low.

Part 4

What was the result of propylthiouracil (PTU) injections on the normal rat’s BMR? Why did this rat construct a palpable goiter? The result of PTU injections on the normal rat was to decrease the BMR. The palpable goiter was as a result of buildup of the precursors of thyroxine. What was the result of PTU injections on the thyroidectomized rat’s BMR? How does the BMR in this case compare through the normal rat’s BMR? Why was this effect observed? The result of PTU injections on the thyroidectomized rat was not visible because tright here was no thyroid gland to be influenced. What was the impact of PTU injections on the hypophysectomized rat’s BMR? How does the BMR in this instance compare through the normal rat’s BMR? Why was this result observed? The impact of PTU injections on the hypophysectomized rat was not visible because the rat is missing the pituitary gland. Activity 2 Plasma Glucose, Insulin, and also Diabetes Mellitus

What is a glucose conventional curve, and also why did you must attain one for this experiment? Did you appropriately predict how you would certainly measure the amount of plasma glucose in a patient sample making use of the glucose traditional curve? The glucose conventional curve correlates the intensity of the color obtained and also measured on a spectrophotometer (optical density) to the glucose concentration. Which patient(s) had glucose reading(s) in the diabetic range? Can you say through certainty whether each of these patients has kind 1 or form 2 diabetes? Why or why not? Patient 3 and also 5 had a fasting plasma glucose in the diabetic variety. Its not possible to tell if they have actually type 1 or type 2 diabetes just from their fasting plasma glucose. 3. Describe the diagnosis for patient 3, who was additionally pregnant at the moment of this assay. This would be described as gestational diabetes which often disappears after the pregnancy. Which patient(s) had actually normal glucose reading(s)?

Patient 1 and also 2 were in normal range.

What are some way of living options these patients through normal plasma glucose readings could recommend to the borderline impaired patients? Limit the ingestion of straightforward sugars. Choose great carbs such as entirety wwarmth and also fiber based carbohydrate options. Exercise regularly.

Activity 3 Hormone Replacement Therapy

Why were ovariectomized rats supplied in this experiment? How does the fact that the rats are ovariectomized explain their baseline T scores? The ovaries create estrogen and also estrogen stimulates bone growth. Without estrogen bone expansion is impaired and osteoporosis is a widespread result. What result did the administration of saline injections have actually on the manage rat? How well did the outcomes compare via your prediction? Saline had actually no result. The inclusion of the saline as an adverse manage is to ensure that saline has actually no effect. What impact did the management of estrogen injections have actually on the estrogen-treated rat? How well did the results compare with your prediction? The estrogen injections did boost the rats vertebral bone thickness and also is suggested by the negative T score.

What impact did the administration of calcitonin injections have on the calcitonin-treated rat? How well did the results compare via your prediction? The calcitonin showed no change in the vertebral bone density. What are some health and wellness risks that postmenopausal woguys need to consider as soon as contemplating estrogen hormone replacement therapy? Health dangers of estrogen therapy encompass an increased incidence of uterine cancer, breastern cancer, and also blood clots. Activity Measuring Cortisol and Adrenocorticotropic Hormone 1 Which patient would the majority of likely be diagnosed through Cushing’s disease? Why? Patient would be diagnosed bc the levels of cortisol and ACTH are both high.

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Which 2 patients have actually hormone levels characteristic of Cushing’s syndrome? Patients 2 and also 5 both have high levels of cortisol and low ACTH. 3 Patient 2 is being treated for rheumatoid arthritis via prednisone. How does this indevelopment adjust the diagnosis? The diagnosis would change to iatrogenic or doctor induced Cushings syndrome. 4 Which patient would certainly most most likely be diagnosed through Addison’s disease? Why? Patient 4 bc the level of ACTH is high but the level of cortisol is low.